I am Head of the Diabetic Foot Unit of the Abano Terme Polyclinic (Padua, Italy) and I have been in this position since the beginning of 2023. Since 2010 I have been part of the team taking care of patients in the ward, treating outpatients and performing surgery (wound treatment, limb salvage, reconstructive surgery, minor and major amputations). I have personally performed over 1,400 surgical interventions and more than 40,000 outpatient visits.
At Abano Polyclinic, and in other clinics, I also work privately, performing visits regarding diabetes, importantly for early detection of cardiovascular risk and complications, in particular regarding the diabetic foot, and endocrinology (thyroid pathologies, menstrual disorders, acne, obesity, hirsutism, polycystic ovary syndrome, osteoporosis, hyper-hypoparathyroidism, hyperprolactinemia, adrenal gland pathologies, secondary hypertension).
At the beginning of 2023 I was appointed Head of the Diabetic Foot Unit of the Abano Terme Polyclinic (Padua, Italy).
I took part in on-line seminars regarding:
Title: Antimicrobial Resistance Patterns in Diabetic Foot Infections, an Epidemiological Study in Northeastern Italy.
Authors: Giovanni Boschetti, Dino Sgarabotto, Marco Meloni, Marino Bruseghin, Christine Whisstock, Mariagrazia Marin, Sasa Ninkovic, Michela Pinfi and Enrico Brocco.
Antibiotics 2021,10, 124.
I took part in on-line seminars regarding:
Title: Multidisciplinary approach for the management and treatment of diabetic foot infections with a reabsorbable, gentamicin-loaded bone graft substitute.
Authors: Christine Whisstock, Antonio Volpe, Sasa Ninkovic, Mariagrazia Marin, Marco Meloni, Marino Bruseghin, Giovanni Boschetti and Enrico Brocco.
J Clin Med. 2020 Nov; 9(11): 3586.
Title: Epidemiological survey of antimicrobial resistances in diabetic foot ulcers.
Authors: Giovanni Boschetti, Marino Bruseghin, Maria Grazia Marin, Sasa Ninkovic, Christine Whisstock, Michela Pinfi, Raffaele Corte, Massimo Solidoro, Enrico Brocco.
Book of abstracts of the 16th Scientific Meeting of the Diabetic Foot Study Group of the EASD (Virtual meeting 18-19 September 2020).
I participated in 15 on-line seminars regarding various topics, the most important being: hypothyroidism, oral contraception, diabetes, polycystic ovary syndrome (PCOS), hypertension guidelines, male infertility, menopause, diabetic neuropathy and ketogenic diet.
Title: Diabetic foot management: multidisciplinary approach for advanced lesion rescue.
Authors: Brocco E, Ninkovic S, Marin M, Whisstock C, Bruseghin M, Boschetti G, Viti R, Forlini W, Volpe A.
J Cardiovasc Surg (Torino). 2018 Oct;59(5):670-684. doi: 10.23736/S0021-9509.18.10606-9. Epub 2018 May 29. Review.
Title: Radiological and clinical outcomes in the medium-term of the use of an antibiotic bone substitute in the diabetic foot.
Authors: Christine Whisstock, Mariagrazia Marin, Sasa Ninkovic, Marino Bruseghin, Giovanni Boschetti, Raffaella Viti, Valeria De Biasio, Enrico Brocco.
Book of abstracts of the 15th Scientific Meeting of the Diabetic Foot Study Group of the EASD (Berlin, 28-30 September 2018).
Book of abstracts of the 37th annual meeting of the European Bone and Joint Infection Society (Helsinki, 6-8 September 2018).
Pubblished on Orthopaedic Proceedings, Vol. 100-B, N. Supp_17.
Title: Maximizing compliance to mid-term offloading in outpatients with recurrent diabetic foot ulcers: tollerability and efficacy of orthotic insoles.
Authors: Giovanni Boschetti, Marino Bruseghin, Christine Whisstock, Mariagrazia Marin, Valentina La Rocca, Deborah Silvestri, Beatrice Macchi, Massimo Solidoro, Sasa Ninkovic, Enrico Brocco.
Book of abstracts of the 15th Scientific Meeting of the Diabetic Foot Study Group of the EASD (Berlin, 28-30 September 2018).
Title: The use of Sodic-Salt DNA fragments in the progression of wounds healing in diabetic foot: a case control study.
Authors: G. Boschetti, M. Marin, S. Ninkovic, C. Whisstock, R. Anichini, M. Bruseghin, M. Manzi, M. Meloni, A. Volpe, M. Pinfi, D. Silvestri, V. La Rocca, B. Macchi, E. Brocco.
Book of abstracts of EWMA (Cracovia, 9-11 May 2018).
Published on The Diabetic Foot Journal, Vol 22 N. 4 2019, pag. 12-16.
Title: A calcium sulphate/hydroxyapatite bone graft substitute eluting gentamicin in the treatment of diabetic foot osteomyelitis: a mid-term follow-up.
Authors: Christine Whisstock, Mariagrazia Marin, Marino Bruseghin, Sasa Ninkovic, Giovanni Boschetti, Antonio Volpe, Enrico Brocco.
Book of abstracts of the 14th Scientific Meeting of the Diabetic Foot Study Group of the EASD (Porto, 8-9 September 2017).
Published on Orthopaedic Proceedings, Vol. 98-B, N. Supp_23.
Title: The use of Sodic-Salt DNA fragments in the progression of wounds healing in diabetic foot: a case control study.
Authors: Mariagrazia Marin, Sasa Ninkovic, Christine Whisstock, Marino Bruseghin, Giovanni Boschetti, Marco Manzi, Mariano Palena, Michela Pinfi, Deborah Silvestri, Valentina La Rocca, Beatrice Macchi, Antonio Volpe, Enrico Brocco.
Book of abstracts of the 14th Scientific Meeting of the Diabetic Foot Study Group of the EASD (Porto, 8-9 September 2017).
Title: Use of a new antibiotic bone substitute to induce healing of osteomyelitis in the diabetic foot.
Authors: Christine Whisstock, Sasa Ninkovic, Mariagrazia Marin, Marino Bruseghin, Antonio Volpe, Marco Manzi, Luis Mariano Palena, Enrico Brocco.
Book of abstracts of the 13th Scientific Meeting of the Diabetic Foot Study Group of the EASD (Stuttgart, 9-11 September 2017).
I participated in 4 on-line seminars regarding hypothyroidism, diabetes and obesity.
Title: Ospedalizzazione per il piede di Charcot nei pazienti diabetici: dati nazionali (Hospitalisation for the Charcot foot in diabetics).
Authors: R. Anichini, F Lombardo, A. De Bellis, A. Tedeschi, S. Viti, C.Whisstock, M.Manzi, E.Brocco, G. Seghieri M. Maggini.
Book of abstracts of the 26° Congresso nazionale SID (Rimini, 4-7 May 2016).
10 on-line seminars regarding different topics, the most important being: neuroendocrine tumours, HIV, cronic deseases, diabetes, allergy and food intollerance, infection from Zika virus.
On 1st October 2015 I gained the position of Specialist Doctor in the Diabetic Foot Unit of the Abano Terme Polyclinic (Padua, Italy).
Title: Use of a new antibiotic bone substitute to induce healing of osteomyelitis in the diabetic foot.
Authors: Christine Whisstock, Sasa Ninkovich, Mariagrazia Marin, Giuseppe Scavone, Marino Bruseghin, Giuliana Di Paolantonio, Marco Manzi, Antonio Volpe, Enrico Brocco.
Book of abstracts of the 5th Annual Oxford Bone Infection Conference (Oxford, 26-27 March 2015).
Book of abstracts of the 34th Annual Meeting of the European Bone and Joint Infection Society (Estoril, Lisbon 10-12 September 2015).
Published on Orthopaedic Proceedings, Vol. 97-B, N. Supp_15.
Title: Cognitive functioning among patients with diabetic foot.
Authors: Marseglia A., Xu W., Rizzuto D., Ferrari C., Whisstock C., Brocco E., Fratiglioni L., Crepaldi G., Maggi S.
J Diabetes Complications. 2014 Nov-Dec;28(6):863-8. doi: 10.1016/j.jdiacomp.2014.07.005. Epub 2014 Jul 15.
Title: Limb salvage with hybrid external/internal fixator in Charcot extreme deformities: ten year follow-up.
Authors: Enrico Brocco, Sasa Ninkovic, Mariagrazia Marin, Christine Whisstock, Andrea Postorino, Andrea Valcarenghi, Filippo Ometto, Davide Varotto, Antonio Volpe.
Book of abstracts of the 11th Meeting of the Diabetic Foot Study Group of the EASD (Sitges, 20-22 September 2013).
Title: L'utilizzo della medicazione avanzata Tenderwet Active® in corso di trattamento di ulcere necrotiche in pazienti con piede diabetico (use of Tenderwet medication during treatment of necrotic ulcers in patients with diabetic foot).
Authors: Marin M.G., Ometto F., Whisstock C., Ninkovic S., Brocco E.
Book of abstracts of the national meeting of the diabetic foot study group (Rome, 30 November-1 December 2012).
Title: Approccio chirurgico in tre steps nella osteomielite di calcagno: un utile presidio per prevenire l'amputazione di gamba (three step surgery in calcaneal osteomyelitis: a useful method of avoiding leg amputation).
Authors: Brocco E., Ninkovic S., Marin M.G, Whisstock C., Ometto F., Sorgentone S., Calore B., Ojeda N.
Book of abstracts of the national meeting of the diabetic foot study group (Rome, 30 November-1 December 2012).
Title: Monitoraggio podologico di pazienti portatori di sostituto dermico (podological monitoring of patients with dermal substitutes).
Authors: Pinfi M., Silvestri D., La Rocca V., Macchi B., Solidoro M., Badan O., Marin M.G, Whisstock C., Ninkovic S., Ometto F., Brocco E.
Book of abstracts of the national meeting of the diabetic foot study group (Rome, 30 November-1 December 2012).
Title: Applicazione di sostituti dermici in pazienti diabetici sottoposti ad amputazioni aperte: studio di una coorte di 229 pazienti (application of dermal substitutes in diabetic patients with open amputations: a cohort study of 229 patients).
Authors: Pinfi M., Silvestri D., La Rocca V., Macchi B., Solidoro M., Badan O., Ninkovic S., Whisstock C., Marin M.G, Ometto F., Brocco E.
Book of abstracts of the national meeting of the diabetic foot study group (Rome, 30 November-1 December 2012).
Title: Three-step surgical intervention for calcaneal osteomyelitis: a useful tool to prevent limb amputations.
Authors: Enrico Brocco, Sasa Ninkovic, Mariagrazia Marin, Christine Whisstock, Filippo Ometto, Nelson Ojeda.
Book of abstracts of the 10th Meeting of the Diabetic Foot Study Group of the EASD (Berlin, 28-30 September 2012).
Title: Reconstruction of the diabetic foot in the elderly.
Authors: A. Volpe, C. Whisstock, E. Brocco.
Book of abstracts of the 9th International Congress of the European Foot and Ankle Society (Noordwijk, 6-8 September 2012).
Title: Caratteristiche cognitive e psicologiche del paziente diabetico complesso (psychological and cognitive characteristics of diabetic patients).
Authors: Marseglia A., Brocco E., Marin M., Limongi F., Whisstock C., Noale M., Maggi S.,
Il giornale di AMD, 2011; 14:103-107
Book of abstracts of the 23° Congresso Nazionale AMD (Rossano Calabro, 25-28 May 2011).
Title: Surgically induced Charcot's neuroarthropaty following single ray amputation in the diabetic foot.
Authors: E. Brocco, B. Mimor, S. Ninkovic, M.G Marin, F. Ometto, B. Calore, N. Ojeda, M. Manzi, S. Sorgentone, Whisstock C.
Book of abstracts of the 9th meeting of the Diabetic Foot Study Group of the EASD (Uppsala, 17-19 September 2010).
Titolo: Efficacia del sostituto dermico Integra nel salvataggio dell'appoggio plantare in amputazioni aperte dell'avampiede nel soggetto diabetico (efficacy of dermal substitute Integra in limb salvage in open forefoot amputations in diabetic patients).
Autori: S. Sorgentone, S. Ninkovic, M.G Marin, N. Ojeda, B. Mimor, B. Calore, F. Ometto, C.Whisstock, E. Brocco.
Book of abstracts of the 9° Congresso Nazionale AIUC (Catania, 15-18 September 2010).
In March 2010 I was appointed as Speciality Doctor in the Diabetic Foot Unit of the Abano Terme Polyclinic (Padua, Italy) in the ward, the outpatient clinic and the operating theatre.
At the same time I started private practice in the Abano Terme Polyclinic (Padua, Italy) covering the Endocrinology, Diabetology and the Diabetic Foot.
I participated in a conferences on the diabetic foot and an update course in angiology for diabetologists.
Between 2006 and 2009 I worked as a specialist at the day clinic of endocrinology and diabetology of San Gerardo Hospital in Monza and I periodically substituted some of the GPs in the local area.
From 2000 to 2009, I cooperated in research run by laboratories directed by prof. Giuseppe Mancia at the Clinical Medical department of San Gerardo Hospital in Monza and at the University of Milano-Bicocca, participating in many clinical trials such as the ADVANCE study, clinical research on hypertension, heart failure, diabetes mellitus and conditions characterised by increased sympathetic nervous system activity.
Title: Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes.
ADVANCE Collaborative Group, (Italy: P. Galli, G. Mancia, F. Paleari, V. Vilei, C. Whisstock).
N Engl J Med. 2008 Jun 12;358(24):2560-72. doi: 10.1056/NEJMoa0802987. Epub 2008 Jun 6.
Title: Efficacia terapeutica di Humalog Mix 50 ter in die versus terapia ottimizzata con insuline umane (3 rapide + 1 intermedia) in pazienti affetti da DM tipo 2 (therapeutic efficacy of Humalog mix 50 three times a day versus optimised therapy with rapid and intermediate human insulin in patients affected by DM type 2).
Authors: Christine Whisstock, Barbara Angeloni, Felice Paleari.
Book of abstracts of the Congresso Nazionale DEI duemila (Villasimius 8-10 May 2008).
Title: Increased arterial stiffness in normoglycemic normotensive offspring of type 2 diabetic parents
Authors: Cristina Giannattasio, Monica Failla, Anna Capra, Elisabetta Scanzani, Maria Amigoni, Lucia Boffi, Christine Whisstock, Pierluigi Gamba, Felice Paleari, Giuseppe Mancia.
Hypertension, 2008; 51:1-2.
Title: Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): a randomised controlled trial.
ADVANCE Collaborative Group: (Italy: P. Galli, G. Mancia, F. Paleari, V. Vilei, C. Whisstock)
Lancet 2007; 370: 829-40.
Title: Effetti di due anni di trattamento con quinapril sullo spessore mio-intimale carotideo in pazienti con diabete mellito tipo 1 (effects of a two year treatment with quinapril on intima media thickness of the carotid artery in type 1 patients).
Authors: Vilei V., Scaranna C., Whisstock C., Capra A., Paleari F., Gamba P., Giannattasio C., Mancia G.
Book of abstracts of the 16° Congresso Nazionale AMD (Sorrento, 21-24 November 2007).
Title: Alterazioni strutturali e funzionali cardiache in figli sani di genitori diabetici (structural and functional heart alterations in offspring of diabetic parents).
Authors: Vilei V., Scaranna C., Capra A., Scotti V., Bernardo S., Paleari F., Gamba P., Whisstock C., Giannattasio C., Mancia G.
Book of abstracts of the 16° Congresso Nazionale AMD (Sorrento, 21-24 November 2007).
Title: Alterazioni strutturali cardiache in figli sani di genitori diabetici (structural heart alterations in offspring of diabetic parents).
Authors: A.Capra, V. Scotti, M. Amigoni, F. Paleari, G. Gamba, C. Whisstock, E. Montemerlo, G. Grosso, C. Giannattasio, G. Mancia.
Book of abstracts of the 24° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Rome, 4-7 October 2007).
Title: Effetti di 2 anni di trattamento con quinapril sullo spessore miointimale carotideo in pazienti con diabete mellito tipo 1 (effects of a two year treatment with quinapril on intima media thickness of the carotid artery in type 1 patients).
Authors: C. Whisstock, L. Viscardi, F. Bianchi, M. Galbiati, A. Capra, P. Gamba, F. Paleari, C., Giannattasio, M. Mancia.
Book of abstracts of the 24° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Rome, 4-7 October 2007).
Title: Relazione tra variabilità della glicemia nelle 24 ore e struttura e funzione delle arterie nel diabete mellito tipo 1 (correlation between glycaemic variability in 24 hours and structure and function of arteries in type 1 diabetes).
Authors: C. Whisstock, M. Alloni, A. Cafro, M. Failla, E. Scanziani, M. Galbiati, F. Paleari, P. Gamba, M. Rigodi, C. Giannattasio, M. Mancia
Book of abstracts of the 24° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Rome, 4-7 October 2007).
Title: Effect of a 2 year treatment with quinapril on carotid intima media in type 1 diabetes mellitus.
Authors: C. Whisstock, L. Viscardi, F. Bianchi, M. Galbiati, A. Capra, P. Gamba, F. Paleari, C. Giannattasio, M. Mancia.
Book of abstracts of the 24° European Meeting on Hypertension (Milan, 15-19 June 2007).
Titolo: Study on 24 hour glycaemia variability and arterial structure and function in type 1 diabetic patients.
Autori: C. Whisstock, M. Alloni, A. Cafro, M. Failla, E. Scanziani, M. Galbiati, F. Paleari, P. Gamba, M. Rigoldi, C. Giannattasio, M. Mancia.
Book of abstracts of the 24° European Meeting on Hypertension (Milan, 15-19 June 2007).
Title: Alterations in cardiac structure in non diabetic offspring of diabetic patients.
Authors: A. Capra, V. Scotti, M. Amigoni, F. Paleari, G. Gamba, C. Whisstock, E. Montemerlo, G. Grosso, C. Giannattasio, G. Mancia.
Book of abstracts of the 24° European Meeting on Hypertension (Milan, 15-19 June 2007).
I participated in three conferences regarding diabetes and prevention of cardiovascular risk.
I specialised in endocrinology with 70/70 cum laude at Milan-Bicocca University, discussing the thesis: Correlation between glycaemia and arterial distensibility measured in 24 hours in patients with type 1 non complicated diabetes (original title: Correlazione tra i valori di glicemia e distensibilità arteriosa misurati nelle 24 ore in pazienti con diabete mellito tipo 1 non complicati).
I participated in four conferences regarding the pharmacological treatment of obesity, diabetes and obesity, hypertension and correlated risk factors and the organisation of team work for patients with high risk factors.
Title: Influenza della pressione ambulatoria delle 24 ore sulla velocità dell’onda di polso: studio di una popolazione generale (influence of 24 h blood pressure on pulse wave velocity).
Authors: Lucia Boffi, Cristina Giannattasio, Davide Corsi, Monica Failla, Gaetano Gentile, Elena Fantini, Christine Whisstock, Rita Facchetti, Luca Beltrame, Michele Bombelli, Ugo Ortiz, Roberto Sega, Giuseppe Mancia.
Book of abstracts of the 64° Congresso Nazionale della Società Italiana di Cardiologia (Rome, 6-10 December 2003).
Title: Influenza della funzione endoteliale sulla rigidità delle arterie nei pazienti con ipertensione essenziale (influence of the endothelial function on arterial rigidity in patients with hypertension).
Authors: Davide Corsi, Cristina Giannattasio, Monica Failla, Elena Fantini, Silvia Maestrini, Lucia Boffi, Anna Capra, Maria Amigoni, Christine Whisstock, Giuseppe Mancia.
Book of abstracts of the 64° Congresso Nazionale della Società Italiana di Cardiologia (Rome, 6-10 December 2003).
Title: Impatto della pressione ambulatoriale delle 24 ore sulla distensibilità carotidea e la velocità dell’onda di polso in una popolazione generale (impact of 24-h blood pressure on carotid distensibility and pulse wave velocity in a general population).
Authors: Boffi L., Giannattasio C., Corsi D., Failla M., Gentile G., Fantini E., Whisstock C., Facchetti R., Beltrame L., Bombelli M., Ortiz U., Sega R., Mancia G.
Book of abstracts of the 20° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Rome 14-17 October 2003).
Title: Distensibilità arteriosa e vasodilatazione flusso mediata nella sclerosi sistemica: effetti del trattamento con PGI2 (arterial distensibility and blood flow dilation in systemic sclerosis: effects of treatment with PGI2).
Authors: G. Gentile, C. Giannattasio, M. Failla, M. Pozzi, M. Gardinali, E. Meles, C. Zazzeron, M. Amigoni, C. Whisstock, A. Capra, G. Mancia.
Book of abstracts of the 20° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Rome, 14-17 October 2003).
Title: La funzione endoteliale influenza la rigidità delle arterie nei pazienti con ipertensione essenziale (the endothelial function influences arterial stiffness in patients with hypertension).
Authors: Corsi D., Giannattasio C., Failla M., Fantini E., Maestroni S., Boffi L., Capra A., Amigoni M., Scotti V., Whisstock C., Mancia G.
Book of abstracts of the 20° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Rome, 14-17 October 2003).
Theoretical and practical course on the diabetic foot (Milan, 28-29 March 2003).
Title: Alterazioni strutturali e funzionali dell’arteria radiale nel diabete mellito tipo 1 e tipo 2 (structural and functional alterations of the radial artery in type 1 and type 2 diabetes).
Authors: C. Whisstock, P. Galli, F. Paleari, P. Gamba, G. Gentile, M. Failla, V. Vilei, C. Giannattasio, G. Mancia.
Book of abstracts of the 8° Congresso interassociativo regionale AMD-SID (Varese, 24-26 October 2002).
Title: Progressivo irrigidimento dell’arteria radiale per reinnervazione dopo trapianto di mano (progressive stiffness of the radial artery concerning reinnervation after a hand transplant).
Authors: M. Failla, C. Giannattasio, M. Lanzetta, S. Lucchina, C. Whisstock, E. Meles, L. Boffi, S. Maestroni, G. Vitale, G. Mancia.
Book of abstracts of the 19° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Bologna, 24-27 September 2002).
Title: Spessore di parete e funzione arteriosa nel diabete mellito tipo 1 e tipo 2 (arterial thickness and function in type 1 diabetes).
Authors C. Giannattasio, C. Whisstock, G. Gentile, P. Gamba, M. Failla, F. Paleari, D. Corsi, E. Fantini, S. Maestroni, G. Mancia.
Book of abstracts of the 19° Congresso Nazionale della Società Italiana di Ipertensione Arteriosa (Bologna, 24-27 September 2002).
I obtained the authority to practise in 2002. I am in the list of members of medical doctors registered at Padua, membership number 10469.
I graduated in medicine at Milan-Bicocca University discussing the thesis "acute hypertriglyceridaemia impairs blood flow dilation in subjects with type IV dyslipidaemia" (original title: l'incremento acuto dei trigliceridi plasmatici riduce la vasodilatazione flusso mediata nella dislipidemia di tipo IV).
Title: Reduction of pulmonary pressure values after alprostadil administration (prostaglandin PGE1) in sclerodermic patients.
Authors: S. Carugo, I. Calchera, M.G. Gorgoglione, N. Grieco, M.R. Pozzi, A. Farina, E. Allevi, C. Addamiano, C. Whisstock, M. Amigoni, C. Giannattasio, G. Mancia.
Book of abstracts of the 11th European Meeting on Hypertension (Milan, Italy, 15-19 June 2001).
I obtained my classical high school diploma at Bartolomeo Zucchi school in Monza.
Medical doctor and endocrinologist, specialised in the treatment of diabetes and of the diabetic foot.
PhD in hypertension and prevention of cardiovascular risk.
Head of the Diabetic Foot Unit of the Abano Terme Polyclinic (Padua, Italy).